What is Duchenne Muscular Dystropy?
It's a recessive X-linked form of musclar dystrophy. The disease qradually weakens the skeletal, or voluntary, muscles in the arms,legs and trunk.
History of Duchenne Muscular Dystropy
DMD was first discovered by a french neurologist Gullaume Benjamin Amand Duchenne in the 1860s. In 1986 researchers found the muteate gene that causes DMD. Not until 1987 the protein associated with the gene was discovered and named dystrophin.
Causes
DMD occurs when a particular gene on the X chromosome fails to make the protein dystrophin.
Diagnose
Doctor checks the patient and family history and perform physical examination to look for a pattern of weakness.
Symptoms
The symptoms usually show before the age of six and may show in infancy. Things like Fatigue,Mental retardation,Muscle weakness( in legs, pelvis, arms, neck and other areas), Difficulty with running,hopping,or jumping, Frequent falls, quickly worsening weakness, progressive difficuty walking.
Treatments
There in no cure for DMD. Treatment is to control the symptoms. Physical therapy is provided to maintain muscle strength and function. In the future they might be able to provide Gene therapy.
Prevention
with about 95% accuracy by gentic studies performed during pregnancy.Genetic counseling is adivised to see if there is a family history of the disorder. DMD can be detected.
Foundations
- Madison Foundation
- Paul Foundation
- Dylansfootprint Foundation
- Jett Foundation
VIDEO: http://www.brainpop.com/health/diseasesinjuriesandconditions/duchennemusculardystrophy/

